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03/15/2010 01:51 PM

Botox injections used to treat overactive bladders

By: Ivanhoe Broadcast Services

An overactive bladder is the result of a sudden and involuntary contraction of the bladder muscle, causing an unstoppable need to urinate.

Botox injections used to treat overactive bladders

An overactive bladder is most common in adults, affecting one in 11 adults in the United States. According to the National Association for Continence, an overactive bladder is a widespread problem that affects people of all ages.

An overactive bladder can cause an uncomfortable quality of life. Sufferers may have the need to urinate more than eight times a day. In these severe cases, a normal lifestyle is prevented.

Research has indicated that people often believe an overactive bladder is a normal part of aging, so symptoms are often overlooked. Less than half of sufferers actually consult a doctor about their symptoms.

According to the National Association for Continence, anticholinergic and bladder muscle relaxant drugs are often prescribed for treating an overactive bladder.

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Several side effects are associated with these drugs, such as dry-mouth, constipation, blurred vision, gastroesophageal reflux and urinary retention. Because of these negative side effects, other treatments are being investigated to improve the lifestyle of those with OAB.

Angelo Gousse, M.D., professor of urology at the University of Miami Miller School of Medicine, is experimenting with using Botox as a treatment for overactive bladder. Botox would be used to relax the muscles of the urinary bladder and deplete the sensation of the bladder.

Urologists from UK Guy's Hospital and King's College London have carried out a double-blind, placebo-controlled trial involving 34 patients using Botox as a treatment for OAB. The study involved 20 injections of Botox totaling 200ml into several areas of the bladder.

For more information

Lisa Worley Media Relations University of Miami Miller School of Medicine (305) 243-5184
Results of the study were measured using a zero to 100 scale. On average, severity of the participant's symptoms decreased by 33 points and the overall impact on their incontinence decreased by 35 points.

Dr. Gousse said according to his research, Botox injections are the simplest solution for an overactive bladder. Botox as a treatment for overactive bladder is expected to be approved by the FDA within the next two years.